Title

Advances in in vivo cell and gene therapy (HIV Cure & Gene Therapy Forum)

Code

SY34

Session Type

Symposium

Track

Not applicable

Channel

IAS+

Date Time

20 July 10:00- 11:30

Local Date Time

10:00 - 11:30 W. Europe Daylight Time

Co-Chairs:

Daiquiri ROBINSON, Penn Center for AIDS Research, United States
Agnieszka CZECHOWICZ, Stanford University, United States

Six presentations by invited speakers will provide a more detailed overview of some of the approaches for targeting and engineering cells in vivo, including efforts to modify hematopoietic stem cells and T cells, or to directly excise proviral HIV genomes from cells in the rebound-competent reservoir.

1 min	Co-chairs introduction Agnieszka CZECHOWICZ, Stanford University, United States Daiquiri ROBINSON, Penn Center for AIDS Research, United States

15 min	HDAd vectors for targeting HSCs in vivo Andre LIEBER, University of Washington, United States

15 min	Progress towards in vivo modification of HSCs by capsid-engineered AAV vectors Hildegard BUENING, Hannover Medical School, Germany

15 min	In vivo targeting of hematopoietic cells with lentiviral vectors Christian BUCHHOLZ, Paul-Ehlich-Institut, Germany

15 min	Excision of HIV proviral genomes in vivo Joachim HAUBER, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Germany

15 min	LNPs targeting HSCs in vivo Sean BURNS, Intellia Therapeutics, United States

14 min	In vivo targeted gene therapy for Sickle Cell Disease Marta ORTEGA-VALLE, GreenLight Biosciences, United States	PDF